Wednesday, March 14, 2007

What is dapagliflozin?

QDIS blogged about Bristol-Myers and AstraZeneca teaming up for a new drug called dapagliflozin. Now, dapagliflozin is, this week, the most used search keyword in Google, leading to Chemical blogspace.

I wondered what the chemical structure of this compound is. The AstraZeneca and Bristol-Myers Squibb websites don't say. Since everything in pharma is patented I went to the US patent database and a search for DPP-4 AND inhibitor found the patents 6,995,183 and 6,995,180. But that does not help me either.

Does anyone know the chemical structure of this compound? Just the InChI would be fine...