Pharmaceutical Bioinformatics

The Wikberg group at Uppsala University where I did my first two years of post-docing in Sweden has a (free) course on pharmaceutical bioinformatics. We worked hard on a course book, which after a year got printed. It ended up with 400 pages, 15 chapters, and 3 appendices. It also includes examples on how to do discussed topics in Bioclipse:

The chapters are:

  1. Introduction

  2. Background

  3. Drug discovery and development

  4. Bioinformatics, drugs and omics

  5. Representing molecules in computers

  6. Representation of 3D structures

  7. Molecular descriptors

  8. Sequence analysis

  9. Macromolecular descriptors

  10. Design of experiments

  11. Data analysis

  12. Databases

  13. QSAR

  14. Proteochemometrics

  15. Semantic web

  16. Answers

And three appendices:

  A. Basic probability theory

  B. Basic matrix algebra

  C. Introduction to Bioclipse

The book is currently undergoing proof review and available to course participants only, and should become available in a couple of months for the general public.