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Saturday, May 28, 2022

new: "The LOTUS initiative for open knowledge management in natural products research"

There is a ton of knowledge still not disclosed in a FAIR way. I am proud to have contributed to this new paper about the new LOTUS initiative for open knowledge management in natural products research (doi:10.7554/eLife.70780). The eLife editor wrote:

The strength of this initiative lies in the effort the authors had put in creating a database that is both reproducible and usable. The result is thus a complete and user-friendly product that will respond to people's needs.

The intrinsic feature of depositing in Wikidata is one of the (many) interesting aspect of LOTUS: wide dissemination is essential and Wikidata fulfills the technical requirements (see also this, this, and this).

The articles shows a number of exciting applications of the increased linked data that results as well as cheminformatics analyses like this Figure 6 from the article:

TMAP visualizations of the chemical diversity present in LOTUS.

Note also this in the caption: An interactive HTML visualization of the LOTUS TMAP is available at https://lotus.nprod.net/post/lotus-tmap/ and archived at https://doi.org/10.5281/zenodo.5801807 . The figure is available under the CC0 license at https://commons.wikimedia.org/wiki/File:Lotus_initiative_1_biologically_interpreted_chemical_tree.svgThe lead authors really went to great lengths to give the reader the best possible reading experience.

Thanks to the lead authors and all co-authors for the great discussions and collaboration!

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